ATHEMETER INJECTION
₦700.00
NOMENCLATURE:
The drug is mainly composed of Artemether. The chemical name is (3R, 5aS, 6R, 8aS, 9R, 10S, 12R, 12aR)-decahydro-10-methoxy-3,6,9-trimethy1-3,12-epoxy-12H-pyrano[4,3-j]-1,2-ben-zodioxepin
CHARACTER:
A colorless or yellowish clear oily solution.
PHARMACOLOGY AND TOXICOLOGY:
Animal pharmacodynamics showed that the drug isa strong schizonticide. Parasitemia clearance occurs rapidly with stable efficacy after administration. It is also effective against chloroquine-resistant P. falciparum malaria. Acute toxicity studies on animals showed that the LD50 of Artemether in mice of a single i.g. administration is 895mg/kg and a single i.m. injection is 296mg/kg; in rats, the LD50 of a single i.m. injection is 597mg/kg. This proves the toxicity of Artemether is quite low.
NOMENCLATURE:
The drug is mainly composed of Artemether. The chemical name is (3R, 5aS, 6R, 8aS, 9R, 10S, 12R, 12aR)-decahydro-10-methoxy-3,6,9-trimethy1-3,12-epoxy-12H-pyrano[4,3-j]-1,2-ben-zodioxepin
CHARACTER:
A colorless or yellowish clear oily solution.
PHARMACOLOGY AND TOXICOLOGY:
Animal pharmacodynamics showed that the drug isa strong schizonticide. Parasitemia clearance occurs rapidly with stable efficacy after administration. It is also effective against chloroquine-resistant P. falciparum malaria. Acute toxicity studies on animals showed that the LD50 of Artemether in mice of a single i.g. administration is 895mg/kg and a single i.m. injection is 296mg/kg; in rats, the LD50 of a single i.m. injection is 597mg/kg. This proves the toxicity of Artemether is quite low.
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